Why St. Lucie County Is the Smartest Place to Lease in 2025

Growth stats, hidden advantages, and what national brands already know

St. Lucie County isn’t just growing. It’s exploding. And if you're a small business owner, franchisee, or service provider looking to secure a long-term lease, 2025 might be your golden window.

Local Growth That Means Business

Over the past five years, St. Lucie County has quietly outpaced larger Florida metros in key economic indicators:

• 13% population growth, compared to 8.9% statewide

• $1B+ in public-private investment, especially around Port St. Lucie and Tradition

• Major expansions from healthcare systems, universities, and research institutes

• A strong job sector driving both demand and stability

This growth isn’t just residential—it’s institutional, commercial, and catalytic. Innovation Square, for example, is home to the next wave of medical and professional service tenants who want to be surrounded by Cleveland Clinic, Torrey Pines, Keiser University, and a booming residential base.

Cleveland Clinic has also added the Lerner Research Institute, expanding its research footprint.Torrey Pines was acquired by Florida International University and is now home to FIU’s Center for Translational Science, further cementing Tradition as a research-forward district.

What Makes St. Lucie County Unique

Here’s what leasing tenants are discovering across the county:

• Tradition’s Hospital & Research Park offers unmatched tenant synergy for health, wellness, and science-based businesses

• Business-friendly zoning and municipality partnerships in both Port St. Lucie and Fort Pierce help streamline permitting and signage

• Fort Pierce adds a commercial and logistical edge with its working deepwater port, ongoing downtown revitalization, and direct rail access

• Home to 3 major national hospitals: HCA Florida Healthcare, Cleveland Clinic, and Tenet Healthcare

• Distribution facilities throughout the county, including major companies like Walmart, Amazon, FedEx, and Cheney Brothers.

• A-rated public schools

Location, Location, and Connection

With direct access to I-95 and the Florida Turnpike, St. Lucie County offers unmatched regional connectivity.

The county’s central location on Florida’s east coast places it within easy reach of Palm Beach, Orlando, and Miami markets—without the congestion or cost.

Unlike many counties to the south that are already densely built out, St. Lucie County still has land available for continued long-term growth and affordable housing.

Ready to Lease in Florida’s Fastest-Growing Corridor?